Characteristic | Description |
---|---|
Active Ingredient | Sildenafil Citrate |
Dosage Forms | Chewable Tablets |
Strength | 100 mg |
Indication | Erectile Dysfunction |
Administration Route | Oral |
More Details on Kamagra Polo |
Pharmacokinetics
Kamagra Polo 100 mg leverages sildenafil citrate as its active compound. Upon oral ingestion, absorption is rapid. Plasma concentrations peak within an hour. The drug exhibits a bioavailability of about 40%. The presence of food can delay absorption, reducing peak plasma levels. The half-life of sildenafil is approximately four hours.
The liver’s CYP3A4 enzyme system primarily metabolizes sildenafil. The metabolites are excreted in feces and urine. Sildenafil’s elimination follows a two-phase process. After initial rapid clearance, a slower terminal phase ensues. These pharmacokinetic properties influence the drug’s onset and duration of action.
Mechanism of Action
Sildenafil, the active ingredient in Kamagra Polo, functions as a phosphodiesterase type 5 (PDE5) inhibitor. It boosts nitric oxide levels. This enhances cyclic guanosine monophosphate (cGMP) concentrations. Elevated cGMP causes smooth muscle relaxation in the corpus cavernosum.
Vasodilation results from this muscular relaxation. It fosters blood flow into penile tissues. Thus, sildenafil facilitates erection upon sexual stimulation. The drug does not directly trigger erection; rather, it enhances the body’s response to sexual arousal.
Indications
Kamagra Polo 100 mg serves a primary role in treating erectile dysfunction (ED). ED affects many men globally. By enhancing blood flow, Kamagra Polo effectively addresses this condition. It allows improved erectile function during sexual activity.
The drug’s chewable form offers convenience. It provides an alternative for those who find traditional tablets cumbersome. Patients should consult healthcare professionals for tailored advice.
Pregnancy and Breastfeeding
Sildenafil is not typically prescribed to women, especially during pregnancy or lactation. Its effects on fetal development remain unclear. Studies have not sufficiently addressed potential risks during pregnancy.
Breastfeeding mothers should exercise caution. Data on sildenafil’s secretion in human milk is limited. Consultations with healthcare providers are imperative before any use during these periods.
Toxicity
Kamagra Polo 100 mg, like any medication, carries potential risks. Overdose may lead to serious health concerns. Symptoms can include visual disturbances, dizziness, and severe hypotension.
Immediate medical attention is crucial in overdose scenarios. Additionally, certain medications and health conditions may interact adversely with sildenafil. Physicians should evaluate patient history before prescribing.
To mitigate risks, adherence to prescribed dosages is paramount. Patients should report any adverse reactions to their healthcare providers promptly.
Potential Side Effects | Description |
---|---|
Headache | Commonly reported symptom. |
Dizziness | May occur with blood pressure changes. |
Flushing | Caused by increased blood flow. |
Nasal Congestion | Due to mucous membrane swelling. |
- Seek professional advice before use.
- Avoid combining with nitrate medications.
- Report any severe side effects immediately.
Data source:
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